van Steensel lab


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Publications Van Steensel Lab

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation.
Peric-Hupkes D, Meuleman W, Pagie L, Bruggeman SW, Solovei I, Brugman W, Gräf S, Flicek P, Kerkhoven RM, van Lohuizen M, Reinders M, Wessels L, van Steensel B.
Mol Cell. 2010 May 28;38(4):603-13.
 

Genome-nuclear lamina interactions and gene regulation.
Kind J, van Steensel B.
Curr Opin Cell Biol. 2010 May 3. [Epub ahead of print]
 

Reassessing the abundance of H3K9me2 chromatin domains in embryonic stem cells.
Filion GJ, van Steensel B.
Nat Genet. 2010 Jan;42(1):4; author reply 5-6.
 

Histone H1 binding is inhibited by histone variant H3.3.
Braunschweig U, Hogan GJ, Pagie L, van Steensel B.
EMBO J. 2009 Dec 2;28(23):3635-45. Epub 2009 Oct 15.
 

High-resolution mapping of heterochromatin redistribution in a Drosophila position-effect variegation model.
Vogel MJ, Pagie L, Talhout W, Nieuwland M, Kerkhoven RM, van Steensel B.
Epigenetics Chromatin. 2009 Jan 29;2(1):1
 

Chromatin domains in higher eukaryotes: insights from genome-wide mapping studies.
de Wit E, van Steensel B.
Chromosoma. 2008 Oct 14.
 

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions.
Guelen L, Pagie L, Brasset E, Meuleman W, Faza MB, Talhout W, Eussen BH, de Klein A, Wessels L, de Laat W, van Steensel B.
Nature. 2008 Jun 12;453(7197):948-51. Epub 2008 May 7.
 

Global chromatin domain organization of the Drosophila genome.
de Wit E, Braunschweig U, Greil F, Bussemaker HJ, van Steensel B.
PLoS Genet. 2008 Mar 28;4(3):e1000045.
 

Linking cohesin to gene regulation.
Peric-Hupkes D, van Steensel B.
Cell. 2008 Mar 21;132(6):925-8. Review.
 

SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila.
Pindyurin AV, Moorman C, de Wit E, Belyakin SN, Belyaeva ES, Christophides GK, Kafatos FC, van Steensel B, Zhimulev IF.
J Cell Sci. 2007 Jul 15;120(Pt 14):2344-51.
 

Detection of in vivo protein-DNA interactions using DamID in mammalian cells.
Vogel MJ, Peric-Hupkes D, van Steensel B.
Nat Protoc. 2007;2(6):1467-78.
 

High-resolution mapping reveals links of HP1 with active and inactive chromatin components.
de Wit E, Greil F, van Steensel B.
PLoS Genet. 2007 Mar 2;3(3):e38.
 

HP1 controls genomic targeting of four novel heterochromatin proteins in Drosophila.
Greil F, de Wit E, Bussemaker HJ, van Steensel B.
EMBO J. 2007 Feb 7;26(3):741-51. Epub 2007 Jan 25.
 
Prospero Acts as a Binary Switch between Self-Renewal and Differentiation in Drosophila Neural Stem Cells.
Choksi SP, Southall TD, Bossing T, Edoff K, de Wit E, Fischer BE, van Steensel B, Micklem G, Brand AH.
Dev Cell. 2006 Dec;11(6):775-789.
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C).
Simonis M, Klous P, Splinter E, Moshkin Y, Willemsen R, de Wit E, van Steensel B, de Laat W.
Nat Genet. 2006 Nov;38(11):1348-54. Epub 2006 Oct 8.
Human Heterochromatin Proteins form Large Domains Containing KRAB-ZNF Genes.
Vogel MJ, Guelen L, de Wit E, Peric Hupkes D, Lodén M, Talhout W, Feenstra M, Abbas B, Classen A-K, van Steensel B.
 Genome Res. 2006 Dec;16(12):1493-504. Epub 2006 Oct 12.
DamID: Mapping of In Vivo Protein–Genome Interactions Using Tethered DNA Adenine Methyltransferase.
Greil F, Moorman C, van Steensel B.
Methods Enzymol 2006; 410:342-359. Epub 2006 Aug 29.
 
Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster.
Moorman C, Sun LV, Wang J, de Wit E, Talhout W, Ward LD, Greil F, Lu X-J, White KP, Bussemaker HJ, van Steensel B.
Proc Natl Acad Sci USA 2006 Aug 8; 103(32):12027-12032. Epub 2006 July 31.
Characterization of the Drosophila melanogaster genome at the nuclear lamina.
Pickersgill H, Kalverda B, de Wit E, Talhout W, Fornerod M, van Steensel B.
 Nat Genet. 2006 Sep;38(9):1005-14. Epub 2006 Jul 30.
Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.
Tolhuis B, Muijrers I, de Wit E, Teunissen H, Talhout W, van Steensel B, van Lohuizen M.
Nat Genet. 2006 Jun;38(6). Epub 2006 April 20.
Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex.
Gilfillan GD, Straub T, de Wit E, Greil F, Lamm R, van Steensel B, Becker PB.
Genes Dev. 2006 Apr 1;20(7):858-70. Epub 2006 Mar 17.
Genome-wide HP1 binding in Drosophila: Developmental plasticity and genomic targeting signals.
de Wit, E, Greil F, van Steensel B.
 Genome Res. 2005 Sep; 15(9):1265-73. Epub 2005 Aug 18.
Histone modifications: from genome-wide maps to functional insights.
van Leeuwen F, van Steensel B.
Genome Biol. 2005;6(6):113. Epub 2005 May 31.
Mapping of genetic and epigenetic regulatory networks using microarrays.
van Steensel B.
Nat Genet. 2005 Jun; 37(6 Suppl): S18-S24.
Whole-genome views of chromatin structure.
Lodén M, van Steensel B.
Chromosome Res. 2005 Jan; 13(3): 289-298.
Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location.
Greil F, van der Kraan I, Delrow J, Smothers JF, de Wit E, Bussemaker HJ, van Driel R, Henikoff S, van Steensel B.
Genes Dev. 2003 Nov 15;17(22):2825-38.
Supplementary material.
Epigenomic profiling using microarrays.
van Steensel B, Henikoff S.
Biotechniques. 2003 Aug;35(2):346-50, 352-4, 356-7.
Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila.
Sun LV, Chen L, Greil F, Negre N, Li TR, Cavalli G, Zhao H, Van Steensel B, White KP.
Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9428-33. Epub 2003 Jul 22.
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network.
Orian A, van Steensel B, Delrow J, Bussemaker HJ, Li L, Sawado T, Williams E, Loo LW, Cowley SM, Yost C, Pierce S, Edgar BA, Parkhurst SM, Eisenman RN.
Genes Dev. 2003 May 1;17(9):1101-14. Epub 2003 Apr 14.
Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding.
van Steensel B, Delrow J, Bussemaker HJ.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2580-5. Epub 2003 Feb 24.
Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing.
Schubeler D, Scalzo D, Kooperberg C, van Steensel B, Delrow J, Groudine M.
Nat Genet. 2002 Nov;32(3):438-42. Epub 2002 Sep 30.
Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3.
Tompa R, McCallum CM, Delrow J, Henikoff JG, van Steensel B, Henikoff S.
Curr Biol. 2002 Jan 8;12(1):65-8.
Chromatin profiling using targeted DNA adenine methyltransferase.
van Steensel B, Delrow J, Henikoff S.
Nat Genet. 2001 Mar;27(3):304-8.
Supplementary material.
Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase.
van Steensel B, Henikoff S. Nat Biotechnol. 2000 Apr;18(4):424-8.