Elisabetta Citterio
(Associate Staff Scientist)

Genome integrity and cancer

The focus of our studies is to understand how cells maintain the stability of their genome. In particular, we are interested in the mechanisms regulating DNA repair and DNA damage signaling in the context of the chromatin environment, and in how deregulation of such mechanisms impacts on tumor development and on stem cell maintenance. To achieve these goals we are using a wide range of (mammalian) cell-based methods for DNA damage signaling/DNA repair, as well as biochemical proteomic approaches and genetically engineered mouse models.

Our group works in close collaboration with the lab of Maarten van Lohuizen. The van Lohuizen lab has large expertise in the generation and analysis of mouse models for cancer and in stem cell biology.

For further information check out our research pages.

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