Publications


Bernike Kalverda, Helen Pickersgill, Victor V. Shloma and Maarten Fornerod (2010). Nucleoporins directly stimulate expression of developmental and cell cycle genes inside the nucleoplasm. Cell, 140:360-71.


Svetlana Atasheva, Alexander Fish, Maarten Fornerod* and Elena I. Frolova1* (2010). Venezuelan Equine Encephalitis Virus Capsid Protein Forms a Tetrameric Complex with CRM1 and Importin α/β that Obstructs Nuclear Pore Complex Function. J Virol. 2010 Feb 10. *co-corresponding authors.


Nikos Xylourgidis, Maarten Fornerod (2009). Acting out of character: regulatory roles of nuclear pore complex proteins. Dev Cell. 17:617-25.


Christina Gontan, Thomas Güttler, Engelen E, Demmers J, Maarten Fornerod, Frank Grosveld, Dick Tibboel, Dirk Görlich, Raymond Poot, Robbert Rottier ( 2009). Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J. Cell Biol. 185:27-34


Kim De Keersmaecker, Jennifer L. Rocnik, Rafael Bernad, Benjamin H. Lee, Dena Leeman, Olga Gielen, Hanne Verachtert, Cedric Folens, Sebastian Munck, Peter Marynen, Maarten Fornerod*, D. Gary Gilliland*, Jan Cools* (2008). Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore. Mol. Cell, 31:134-42. * co-corresponding authors


Floor Frederiks, Manuel Tzouros, Gideon Oudgenoeg, Tibor van Welsem, Maarten Fornerod, Jeroen Krijgsveld and Fred van Leeuwen (2008). Non-processive methylation by Dot1 leads to redundant functions of mono-, di-, and trimethylated histone H3K79. Nat. Struc. Mol. Biol. 15:550-7.

Jolita Hendriksen, Marnix Jansen, Carolyn M Brown, Hella Van der Velde, Marco Van Ham, Niels Galjart, Johan Offerhaus, Francois Fagotto, and Maarten Fornerod (2008). Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway. J. Cell Sci. 121:1793-1802. Reprint (limited download)

Bernike Kalverda, Michael D. Roling and Maarten Fornerod (2008). Chromatin organization in relation to the nuclear periphery. FEBS Lett., PMID: 18435921. Review.

Dieuwke Engelsma, Noelia Valle, Alexander Fish, Nathalie Salome, Jose M. Almendral and Maarten Fornerod (2008). A supraphysiological nuclear export signal is required for parvovirus nuclear export. Mol Biol Cell 10:2544-2552.

Maarten Fornerod and Paul R. Clarke (2008). To the Centre of the Volcano: Mechanisms of Nucleocytoplasmic Transport. EMBO Rep. 9: 419-424. Meeting report.

Van Vlierberghe P, van Grotel M, Tchinda J, Lee C, Beverloo HB, van der Spek PJ, Stubbs A, Cools J, Nagata K, Fornerod M, Buijs-Gladdines J, Horstmann M, van Wering ER, Soulier J, Pieters R, Meijerink JP (2008). The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia. Blood 111:4668-4680.

Stijn Heessen and Maarten Fornerod (2007). The inner nuclear envelope as transcription factor resting place. EMBO Rep 8:914-919. Review.

Dieuwke Engelsma, Jose A. Rodriguez, Alexander Fish, Giuseppe Giaccone and Maarten Fornerod (2007). Homodimerization antagonizes nuclear export of Survivin. Traffic 8:1495-502.

Bernike Kalverda and Maarten Fornerod (2007). The nuclear life of nucleoporins. Dev Cell 13:164-5. Preview.

Helen Pickersgill, Bernike Kalverda, Elzo de Wit, Wendy Talhout, Maarten Fornerod*, Bas van Steensel* (2006). Characterization of the Drosophila genome at the nuclear lamina. Nat genet 38:1005-1014. *co-corresponding authors.

Rafael Bernad, Dieuwke Engelsma, Helen Sanderson, Helen Pickersgill, and Maarten Fornerod (2006). The Nup214/Nup88 nucleoporin subcomplex is required for CRM1 mediated 60S preribosomal nuclear export. J Biol Chem. 281: 19378-86.

Jolita Hendriksen, Francois Fagotto, Hella van der Velde, Martijn van Schie, Jasprien Noordermeer and Maarten Fornerod (2005). RanBP3 enhances nuclear export of active β-Catenin independently of CRM1. J Cell Biol, 171:785-797.

Urs Greber and Maarten Fornerod (2005). Nuclear import in viral infections. Curr Top Microbiol Immunol. 285:109-138. Review.

Dieuwke Engelsma, Rafael Bernad, Jero Calafat and Maarten Fornerod (2004). Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358. EMBO J. 15:3643-52.

Rafael Bernad, Hella Van Der Velde, Maarten Fornerod and Helen Pickersgill (2004) Nup358/RanBP2 attaches to the NPC via association with Nup88 and Nup214/CAN, and plays a supporting role in CRM1-mediated nuclear protein export. Mol. Cel. Biol. 24:2373-2384.

Peggy Roth, Nicos Xylourgidis, Sabri N, Anne Uv, Maarten Fornerod, and Cristos Samakovlis (2003). The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export. J Cell Biol. 163:701-706.

Tobias C. Walther, Helen S. Pickersgill, Volker C. Cordes, Martin W. Goldberg, Terry D. Allen, Iain W. Mattaj and Maarten Fornerod (2002). The cytoplasmic filaments of the nuclear pore complex are dispensible for selective nuclear import. J. Cell Biol., 158: 63-77.

Maarten Fornerod and Mustuhito Ohno (2002). Exportin-mediated nuclear export of proteins and ribonuleoproteins. Res. Probl. Cell Diff. 35:67-91. Review.

Lloyd C. Trotman, Nicole Mosberger, Maarten Fornerod, Robert P. Stidwill and Urs F. Greber (2001). Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1. Nat. Cell Biol. 12: 1092-1100.

Tobias C. Walther, Maarten Fornerod, Helen Pickersgill, Martin Goldberg, Terry D. Allen and Iain W. Mattaj (2001). The Nucleoporin Nup153 is Requred for Nuclear Pore Basket Formation, Nuclear pore Complex Anchoring and Import of a Subset of Nuclear Proteins. EMBO J. 20:5703-5714.

Ludwig Englmeier, Maarten Fornerod, F. Ralf Bischoff, Carlo Petosa, Iain W. Mattaj and Ulrike Kutay (2001). RanBP3 facilitates nuclear protein export by stabilising the interaction between certain export substrates and CRM1. EMBO Rep. 2:926-932.

Jörg Hamm and Maarten Fornerod (2000). Anti-idiotype RNAs that mimic the leucine-rich nuclear export signal and specifically bind to CRM1/exportin 1. Chem. Biol. 7:345-54.

Peter Askjaer, Angela Bachi, Matthias Wilm, Ralf Bischoff, Daniel Weeks, Vera Ogniewski, Mutsuhito Ohno, Christof Niehrs, Jorgen Kjems, Iain W. Mattaj and Maarten Fornerod (1999). RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase. Mol. Cell. Biol. 19: 6276-6285.

Colin Pritchard, Fornerod M., Lawryn L. Kasper, and Jan M. van Deursen (1999). RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains. J. Cell Biol. 145:237-54.

Fortes P, Bilbao-Cortes D, Fornerod M, Rigaut G, Raymond W, Seraphin B, Mattaj IW (1999). Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition. Genes Dev. 13:2425-2438.

Fortes P, Kufel J, Fornerod M, Polycarpou-Schwarz M, Lafontaine D, Tollervey D, Mattaj IW (1999). Genetic and physical interactions involving the yeast nuclear cap-binding complex. Mol Cell Biol. 19:6543-6553.

Gert-Jan Arts, Maarten Fornerod and Iain W. Mattaj (1998). Identification of a nuclear export receptor for tRNA. Curr. Biol. 8:305-14.

Mutsohito Ohno, Maarten Fornerod and Iain W. Mattaj (1998). Nucleocytoplasmic transport: the last 200 nanometers. Cell 92:327-36. Review.

Maarten Fornerod, Mutsohito Ohno, Mironu Yoshida and Iain W. Mattaj (1997b). CRM1 is a nuclear export receptor for leucine-rich nuclear export signals. Cell 90: 1051-1060.

Maarten Fornerod, Jan van Deursen, Sjozèf van Baal, Donna Davis, K. Gopal Murti and Gerard Grosveld (1997a). The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. EMBO J. 16: 807-816.

Fornerod M, van Baal S, Valentine V, Shapiro DN, Grosveld G ( 1997). Chromosomal localization of genes encoding CAN/Nup214-interacting proteins--human CRM1 localizes to 2p16, whereas Nup88 localizes to 17p13 and is physically linked to SF2p32. Genomics 42:538-540.

Bonten E, van der Spoel A, Fornerod M, Grosveld G, d'Azzo A (1996). Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis. Genes Dev. 10:3156-3169.

Fornerod M, Boer J, van Baal S, Morreau H, Grosveld G (1996). Interaction of cellular proteins with the leukemia specific fusion proteins DEK-CAN and SET-CAN and their normal counterpart, the nucleoporin CAN. Oncogene. 1996 Oct 17;13(8):1801-1808.

Yang Y, Vanin EF, Whitt MA, Fornerod M, Zwart R, Schneiderman RD, Grosveld G, Nienhuis AW (1995). Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein. Hum Gene Ther. 6:1203-1213.

Van Deursen J, Fornerod M, Van Rees B, Grosveld G (1995). Cre-mediated site-specific translocation between nonhomologous mouse chromosomes. Proc Natl Acad Sci U S A. 92:7376-7380.

Fornerod M, Boer J, van Baal S, Jaegle M, von Lindern M, Murti KG, Davis D, Bonten J, Buijs A, Grosveld G (1995). Relocation of the carboxyterminal part of CAN from the nuclear envelope to the nucleus as a result of leukemia-specific chromosome rearrangements. Oncogene. 10:1739-1748.

Koken MH, Odijk HH, van Duin M, Fornerod M, Hoeijmakers JH. (1993).Augmentation of protein production by a combination of the T7 RNA polymerase system and ubiquitin fusion: overproduction of the human DNA repair protein, ERCC1, as a ubiquitin fusion protein in Escherichia coli. Biochem Biophys Res Commun. 195:643-653.

Hensgens LA, Fornerod M, Rueb S, Winkler AA, van der Veen S, Schilperoort RA (1992).Translation controls the expression level of a chimaeric reporter gene. Plant Mol Biol. 20:921-38.

von Lindern M, Fornerod M, Soekarman N, van Baal S, Jaegle M, Hagemeijer A, Bootsma D, Grosveld G. (1992). Translocation t(6;9) in acute non-lymphocytic leukaemia results in the formation of a DEK-CAN fusion gene. Baillieres Clin Haematol. 5:857-79.

von Lindern M, Fornerod M, van Baal S, Jaegle M, de Wit T, Buijs A, Grosveld G. (1992). The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell Biol. 12:1687-1697. Review.