NKI-AVL publications 2006

list dated 26 January 2007

(1) Aalders MCG, Triesscheijn M, Ruevekamp M, de Bruin M, Baas P, Faber DJ, Stewart FA. Doppler optical coherence tomography to monitor the effect of photodynamic therapy on tissue morphology and perfusion. J Biomed Optics 2006; 11:044011

(2) Aarts M, Dekker M, de Vries S, van der Wal A, te Riele H. Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells. Nucleic Acids Res 2006; 34:e147

(3) Abdullah-Sayani A, Bueno-de-Mesquita JM, Van De Vijver MJ. Technology insight: Tuning into the genetic orchestra using microarrays - Limitations of DNA microarrays in clinical practice. Nat Clin Pract Oncol 2006; 3:501-516

(4) Adam M, Pogacic V, Bendit M, Chappuis R, Nawijn MC, Duyster J, Fox CJ, Thompson CB, Cools J, Schwaller J. Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of Fms-like tyrosine kinase 3 and BCR/ABL. Cancer Res 2006; 66:3828-3835

(5) Adler AS, Lin M, Horlings H, Nuyten DSA, Van De Vijver MJ, Chang HY. Genetic regulators of large-scale transcriptional signatures in cancer. Nat Genet 2006; 38:421-430

(6) Albeck S, Alzari P, Andreini C, Banci L, Berry IM, Bertini I, Cambillau C, Canard B, Carter L, Cohen SX, Diprose JM, Dym O, Esnouf RM, Felder C, Ferron F, Guillemot F, Hamer R, Ben Jelloul M, Laskowski RA, Laurent T, Longhi S, Lopez R, Luchinat C, Malet H, Mochel T, Morris RJ, Moulinier L, Oinn T, Pajon A, Peleg Y, Perrakis A, Poch O, Prilusky J, Rachedi A, Ripp R, Rosato A, Silman I, Stuart DI, Sussman JL, Thierry JC, Thompson JD, Thornton JM, Unger T, Vaughan B, Vranken W, Watson JD, Whamond G, Henrick K. SPINE bioinformatics and data-management aspects of high-throughput structural biology. Acta Crystallogr D Biol Crystallogr 2006; 62:1184-1195

(7) Alberici P, Jagmohan-Changur S, De Pater E, Van Der Valk M, Smits R, Hohenstein P, Fodde R. Smad4 haploinsufficiency in mouse models for intestinal cancer. Oncogene 2006; 25:1841-1851

(8) Aleman BMP, van den Belt-Dusebout AW, De Bruin ML, van't Veer MB, Baaijens MH, de Boer JP, Hart AA, Klokman WJ, Kuenen MA, Ouwens GM, Bartelink H, van Leeuwen FE. Late cardiotoxicity after treatment for Hodgkin's lymphoma. Blood 2006;[Epub ahead of print]

(9) Altelaar AFM, Klinkert I, Jalink K, De Lange RPJ, Adan RAH, Heeren RMA, Piersma SR. Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry. Anal Chem 2006; 78:734-742

(10) Alzari PM, Berglund H, Berrow NS, Blagova E, Busso D, Cambillau C, Campanacci V, Christodoulou E, Eiler S, Fogg MJ, Folkers G, Geerlof A, Hart D, Haouz A, Herman MD, Macieira S, Nordlund P, Perrakis A, Quevillon-Cheruel S, Tarandeau F, van Tilbeurgh H, Unger T, Luna-Vargas MPA, Velarde M, Willmanns M, Owens RJ. Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE. Acta Crystallogr D Biol Crystallogr 2006; 62:1103-1113

(11) Andrieu N, Easton DF, Chang-Claude J, Rookus MA, Brohet R, Cardis E, Antoniou AC, Wagner T, Simard J, Evans G, Peock S, Fricker JP, Nogues C, Van't Veer L, van Leeuwen FE, Goldgar DE. Effect of chest X-rays on the risk of breast cancer among BRCA1/2 mutation carriers in the international BRCA1/2 carrier cohort study: a report from the EMBRACE, GENEPSO, GEO-HEBON, and IBCCS Collaborators' Group. J Clin Oncol 2006; 24:3361-3366

(12) Andrieu N, Goldgar DE, Easton DF, Rookus M, Brohet R, Antoniou AC, Peock S, Evans G, Eccles D, Douglas F, Nogues C, Gauthier-Villars M, Chompret A, van Leeuwen FE, Kluijt I, Benitez J, Arver B, Olah E, Chang-Claude J. Pregnancies, breast-feeding, and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS). J Natl Cancer Inst 2006; 98:535-544

(13) Andrieux A, Salin P, Schweitzer A, gou M, Pachoud B, Brun P, Gory F, Kujala P, Suaud-Chagny MF, fle G, Job D. Microtubule Stabilizer Ameliorates Synaptic Function and Behavior in a Mouse Model for Schizophrenia. Biol Psychiatry 2006; 60:1224-1230

(14) Appels NMGM, Tung KO, Rosing H, Schellens JHM, Beijnen JH. A rapid and simple HPLC-UV method for the determination of inhibition characteristics of farnesyl transferase inhibitors. Biomed Chromatogr 2006; 20:161-165

(15) Appels NMGM, Rosing H, Stephens TC, Hughes A, Schellens JHM, Beijnen JH. Absolute quantification of farnesylated Ras levels in complex samples using liquid chromatography fractionation combined with tryptic digestion and electrospray tandem mass spectrometry. Anal Biochem 2006; 352:33-40

(16) Appels NMGM, Rosing H, Stephens TC, Schellens JHM, Beijnen JH. Quantification of farnesylmethylcysteine in lysates of peripheral blood mononuclear cells using liquid chromatography coupled with electrospray tandem mass spectrometry: Pharmacodynamic assay for farnesyl transferase inhibitors. Anal Chem 2006; 78:2617-2622

(17) Aricescu AR, Assenberg R, Bill RM, Busso D, Chang VT, Davis SJ, Dubrovsky A, Gustafsson L, Hedfalk K, Heinemann U, Jones IM, Ksiazek D, Lang C, Maskos K, Messerschmidt A, Macieira S, Peleg Y, Perrakis A, Poterszman A, Schneider G, Sixma TK, Sussman JL, Sutton G, Tarboureich N, Zeev-Ben-Mordehai T, Jones EY. Eukaryotic expression: Developments for structural proteomics. Acta Crystallogr D Biol Crystallogr 2006; 62:1114-1124

(18) Armstrong NJ, Mcpeek MS, Speed TP. Incorporating interference into linkage analysis for experimental crosses. Biostatistics 2006; 7:374-386

(19) Armstrong NJ, Brodnicki TC, Speed TP. Mind the gap: Analysis of marker-assisted breeding strategies for inbred mouse strains. Mamm Genome 2006; 17:273-287

(20) As-Brooks CJ, Koopmans-van Beinum FJ, Pols LCW, Hilgers FJM. Acoustic Signal Typing for Evaluation of Voice Quality in Tracheoesophageal Speech. J Voice 2006; 20:355-368

(21) Aulwurm S, Wischhusen J, Friese M, Borst J, Weller M. Immune stimulatory effects of CD70 override CD70-mediated immune cell apoptosis in rodent glioma models and confer long-lasting antiglioma immunity in vivo. Int J Cancer 2006; 118:1728-1735

(22) Baas P, Belderbos JSA, Senan S, Kwa HB, Van Bochove A, Van Tinteren H, Burgers JA, van Meerbeeck JP. Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: A Dutch multicenter phase II study. Br J Cancer 2006; 94:625-630

(23) Baas P, Triesscheijn M, Burgers S, Van Pel R, Stewart F, Aalders M. Fluorescence detection of pleural malignancies using 5-aminolaevulinic acid. Chest 2006; 129:718-724

(24) Baas P, van't Hullenaar N, Wagenaar J, Kaajan JPG, Koolen M, Schrijver M, Schlösser N, Burgers JA. Occupational asbestos exposure: How to deal with suspected mesothelioma cases - The Dutch approach. Ann Oncol 2006; 17:848-852

(25) Bahar M, Ballard C, Cohen SX, Cowtan KD, Dodson EJ, Emsley P, Esnouf RM, Keegan R, Lamzin V, Langer G, Levdikov V, Long F, Meier C, Muller A, Murshudov GN, Perrakis A, Siebold C, Stein N, Turkenburg MGW, Vagin AA, Winn M, Winter G, Wilson KS. SPINE workshop on automated X-ray analysis: a progress report. Acta Crystallogr D Biol Crystallogr 2006; 62:1170-1183

(26) Bajanca F, Luz M, Raymond K, Martins GG, Sonnenberg A, Tajbakhsh S, Buckingham M, Thorsteinsdóttir S. Integrin ?6?1-laminin interactions regulate early myotome formation in the mouse embryo. Development 2006; 133:1635-1644

(27) Bakx R, Emous M, Legemate DA, Zoetmulder FAN, van Tienhoven G, Bemelman WA, van Lanschot JJB. Harm and benefits of short-term pre-operative radiotherapy in patients with resectable rectal carcinomas. Eur J Surg Oncol 2006; 32:520-526

(28) Bakx R, Emous M, Legemate DA, Machado M, Zoetmulder FAN, van Tets WF, Bemelman WA, Slors JFM, van Lanschot JJB. Categorization of major and minor complications in the treatment of patients with resectable rectal cancer using short-term pre-operative radiotherapy and total mesorectal excision: A Delphi round. Colorectal Dis 2006; 8:302-308

(29) Banci L, Bertini I, Cusack S, De Jong RN, Heinemann U, Jones EY, Maskos K, Kozielski F, Owens R, Perrakis A, Siebold C, Silman I, Messerschmidt A, Poterszman A, Schneider G, Sixma T, Sussman JL, Stewart-Jones G, Thierry JC, Moras D. First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value. Acta Crystallogr D Biol Crystallogr 2006; 62:1208-1217

(30) Baricevic I, Jones DR, Malenkovic V, Nedic O. The effect of laparoscopy on the IGF system in patients diagnosed with acute cholecystitis. Clin Endocrinol (Oxf) 2006; 65:373-379

(31) Baricevic I, Jones DR, Nikolic JA, Nedic O. Gastrointestinal inflammation and the circulating IGF system in humans. Horm Metab Res 2006; 38:22-27

(32) Bartelink H. Partial breast irradiation: Is it a valid option? Breast 2006; 15:297-299

(33) Baumert BG, Rutten I, Dehing-Oberije C, Twijnstra A, Dirx MJM, Debougnoux-Huppertz RMTL, Lambin P, Kubat B. A pathology-based substrate for target definition in radiosurgery of brain metastases. Int J Radiat Oncol Biol Phys 2006; 66:187-194

(34) Begg AC. Can the severity of normal tissue damage after radiation therapy be predicted? PLoS Medicine 2006; 3:1713-1714

(35) Belderbos JSA, Heemsbergen WD, De Jaeger K, Baas P, Lebesque JV. Final results of a Phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys 2006; 66:126-134

(36) Belt-Dusebout AW, Nuver J, de Wit R, Gietema JA, Bokkel Huinink WW, Rodrigus PT, Schimmel EC, Aleman BM, van Leeuwen FE. Long-term risk of cardiovascular disease in 5-year survivors of testicular cancer. J Clin Oncol 2006; 24:467-475

(37) Bergink S, Salomons FA, Hoogstraten D, Groothuis TAM, De Waard H, Wu J, Yuan L, Citterio E, Houtsmuller AB, Neefjes J, Hoeijmakers JHJ, Vermeulen W, Dantuma NP. DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. Genes Dev 2006; 20:1343-1352

(38) Bernad R, Engelsma D, Sanderson H, Pickersgill H, Fornerod M. Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export. J Biol Chem 2006; 281:19378-19386

(39) Bernards R, Brummelkamp TR, Beijersbergen RL. shRNA libraries and their use in cancer genetics. Nat Meth 2006; 3:701-706

(40) Bernards R. Exploring the uses of RNAi - Gene knockdown and the nobel prize. N Engl J Med 2006; 355:2391-2393

(41) Bernards R. Nobelprijs Fysiologie of Geneeskunde 2006 voor de ontdekking van RNA-interferentie. Ned Tijdschr Geneeskd 2006; 150:2849-2853

(42) Berns A. Cancer biology: Can less be more for p53? Nature 2006; 443:153-154

(43) Berry IM, Dym O, Esnouf RM, Harlos K, Meged R, Perrakis A, Sussman JL, Walter TS, Wilson J, Messerschmidt A. SPINE high-throughput crystallization, crystal imaging and recognition techniques: current state, performance analysis, new technologies and future aspects. Acta Crystallogr D Biol Crystallogr 2006; 62:1137-1149

(44) Beumer JH, Beijnen JH, Schellens JHM. Mass balance studies, with a focus on anticancer drugs. Clin Pharmacokinet 2006; 45:33-58

(45) Bex A, Kerst M, Mallo H, Meinhardt W, Horenblas S, De Gast GC. Interferon alpha 2b as medical selection for nephrectomy in patients with synchronous metastatic renal cell carcinoma: A consecutive study. Eur Urol 2006; 49:76-81

(46) Bijker N, Meijnen P, Peterse JL, Bogaerts J, Van Hoorebeeck I, Julien JP, Gennaro M, Rouanet P, Avril A, Fentiman IS, Bartelink H, Rutgers EJ. Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ: ten-year results of European Organisation for Research and Treatment of Cancer randomized phase III trial 10853--a study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group. J Clin Oncol 2006; 24:3381-3387

(47) Bloemen-van Gurp EJ, Minken AWH, Mijnheer BJ, Dehing-Oberye CJG, Lambin P. Clinical implementation of MOSFET detectors for dosimetry in electron beams. Radiother Oncol 2006; 80:288-295

(48) Boekhout AH, Beijnen JH, Schellens JHM. Symptoms and treatment in cancer therapy-induced early menopause. Oncologist 2006; 11:641-654

(49) Boelens MC, van den Berg A, Vogelzang I, Wesseling J, Postma DS, Timens W, Groen HJM. Differential expression and distribution of epithelial adhesion molecules in non-small cell lung cancer and normal bronchus. J Clin Pathol 2006;Published online

(50) Boesten LSM, Zadelaar ASM, van Nieuwkoop A, Hu L, Jonkers J, van de Water B, Gijbels MJJ, van der Made I, de Winther MPJ, Havekes LM, van Vlijmen BJM. Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice. FASEB J 2006; 20:953-955

(51) Bogaerts J, Cardoso F, Buyse M, Braga S, Loi S, Harrison JA, Bines J, Mook S, Decker N, Ravdin P, Therasse P, Rutgers E, van't Veer LJ, Piccart M. Gene signature evaluation as a prognostic tool: Challenges in the design of the MINDACT trial. Nat Clin Pract Oncol 2006; 3:540-551

(52) Boogaerts M, Oberhoff C, ten Bokkel Huinink W, Nowrousian MR, Hayward CRW, Burger HU. Epoetin beta (NeoRecormon«) therapy in patients with solid tumours receiving platinum and non-platinum chemotherapy: A meta-analysis. Anticancer Res 2006; 26:479-484

(53) Booman M, Douwes J, Glas AM, Riemersma SA, Jordanova ES, Kok K, Rosenwald A, de Jong D, Schuuring E, Kluin PM. Mechanisms and effects of loss of human leukocyte antigen class II expression in immune-privileged site-associated B-cell lymphoma. Clin Cancer Res 2006; 12:2698-2705

(54) Booman M, Douwes J, Glas AM, de Jong D, Schuuring E, Kluin PM. Primary testicular diffuse large B-cell lymphomas have activated B-cell-like subtype characteristics. J Pathol 2006; 210:163-171

(55) Boot H, Jansen EPM, Cats A. Treatment of gastric cancer [5]. N Engl J Med 2006; 355:1387

(56) Borchert A, Chi CW, Ufer C, Schiebel H, Savaskan NE, Kuhn H. The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis. J Biol Chem 2006; 281:19655-19664

(57) Borst P, Zelcer N, Van De Wetering K. MRP2 and 3 in health and disease. Cancer Lett 2006; 234:51-61

(58) Borst P, Zelcer N, Van De Wetering K, Poolman B. On the putative co-transport of drugs by multidrug resistance proteins. FEBS Lett 2006; 580:1085-1093

(59) Borst P, Genest PA. Parasitology: Switching like for like. Nature 2006; 439:926-927

(60) Borst P, de Wolf CJF, Van De Wetering K. Multidrug resistance-associated proteins 3, 4, and 5. Pflugers Arch 2006;Published online

(61) Borst P, Wielinga P. Pumping Out Drugs: The Potential Impact of ABC Transporters on Resistance to Base, Nucleoside, and Nucleotide Analogs. In: Peters GJ, editor. Deoxynucleoside Analogs in Cancer Therapy. Totowa, NJ.: Humana Press, 2006: 109-118

(62) Borst P. From cancer cells to trypanosomes and back again. Cellular and molecular life sciences : CMLS 2006; 63:745-754

(63) Bos E, Bomans P, De Haas F, Voorhout W, Gnaegi H, Frederik P, Hubert D, Peters PJ. Understanding the three-dimensional architecture in terms of spatial arrangements of organelle-bound protein complexes - Our next great challenge. Microsc Microanal 2006; 12:1588

(64) Bosch TM, Deenen M, Pruntel R, Smits PHM, Schellens JHM, Beijnen JH, Meijerman I. Screening for polymorphisms in the PXR gene in a Dutch population. Eur J Clin Pharmacol 2006; 62:395-399

(65) Bosch TM, Meijerman I, Beijnen JH, Schellens JHM. Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer. Clin Pharmacokinet 2006; 45:253-285

(66) Bosch TM, Huitema ADR, Doodeman VD, Jansen R, Witteveen E, Smit WM, Jansen RL, Van Herpen CM, Soesan M, Beijnen JH, Schellens JHM. Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel. Clin Cancer Res 2006; 12:5786-5793

(67) Bosch TM, Doodeman VD, Smits PHM, Meijerman I, Schellens JHM, Beijnen JH. Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population. Mol Diagn Ther 2006; 10:175-185

(68) Bosch TM, Meijerman I, Beijnen JH, Schellens JHM. Genetic polymorphisms of drug metabolising enzymes and drug transporters in relation to cancer risk. Curr Cancer Ther Rev 2006; 2:137-155

(69) Bosga-Bouwer AG, van den Berg A, Haralambieva E, de Jong D, Boonstra R, Kluin P, van den Berg E, Poppema S. Molecular, cytogenetic, and immunophenotypic characterization of follicular lymphoma grade 3B; a separate entity or part of the spectrum of diffuse large B-cell lymphoma or follicular lymphoma? Hum Pathol 2006; 37:528-533

(70) Bottomley A, Gaafa R, Manegold C, Burgers S, Coens C, Legrand C, Vincent M, Giaccone G, Van Meerbeeck J. Short-Term Treatment-Related Symptoms and Quality of Life: Results From an International Randomized Phase III Study of Cisplatin With or Without Raltitrexed in Patients With Malignant Pleural Mesothelioma: An EORTC Lung-Cancer Group and National Cancer Institute, Canada, Intergroup Study. J Clin Oncol 2006; 24:1435-1442

(71) Boyle P, Ariyaratne MAY, Barrington R, Bartelink H, Bartsch G, Berns A, de Valeriola D, Dinshaw KA, Eggermont AMM, Gray N, Kakizoe T, Singh Karki B, Kaslar M, Kerr DJ, Khayat D, Khuhaprema T, Kim IH, Martin-Moreno J, McVie G, Park JG, Philip T, Ringborg U, Rodger A, Seffrin JR, Semiglazov V, Soo KC, Sun Y, Thomas R, Tursz T, Veronesi U, Wiestler O, Yoo KY, Zatonski W, Zhao P. Tobacco: deadly in any form or disguise. Lancet 2006; 367:1710-1712

(72) Brandon EFA, Sparidans RW, Guijt KJ, Löwenthal S, Meijerman I, Beijnen JH, Schellens JHM. In vitro characterization of the human biotransformation and CYP reaction phenotype of ET-743 (Yondelis«, Trabectidin«), a novel marine anti-cancer drug. Invest New Drugs 2006; 24:3-14

(73) Brandon EFA, Bosch TM, Deenen MJ, Levink R, Van Der Wal E, Van Meerveld JBM, Bijl M, Beijnen JH, Schellens JHM, Meijerman I. Validation of in vitro cell models used in drug metabolism and transport studies; Genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines. Toxicol Appl Pharmacol 2006; 211:1-10

(74) Brandsma D, Taphoorn MJB, De Jager W, Bonfrer H, Algra A, Reijneveld JC, Boogerd W, Korse T, Verbeek MM, Rijkers GT, Voest EE. Interleukin-8 CSF levels predict survival in patients with leptomeningeal metastases. Neurology 2006; 66:243-246

(75) Brandsma D, Voest EE, De Jager W, Bonfrer H, Algra A, Boogerd W, Korse T, Reijneveld JC, Verbeek MM, Rijkers G, Taphoorn MJB. CSF protein profiling using Multiplex Immuno-assay: A potential new diagnostic tool for leptomeningeal metastases. J Neurol 2006; 253:1177-1184

(76) Breedveld P, Beijnen JH, Schellens JHM. Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs. Trends Pharmacol Sci 2006; 27:17-24

(77) Broekhuizen LN, Wijsman JH, Peterse JL, Rutgers EJT. The incidence and significance of micrometastases in lymph nodes of patients with ductal carcinoma in situ and T1a carcinoma of the breast. Eur J Surg Oncol 2006; 32:502-506

(78) Brouwers EEM, Tibben MM, Rosing H, Hillebrand MJX, Joerger M, Schellens JHM, Beijnen JH. Sensitive inductively coupled plasma mass spectrometry assay for the determination of platinum originating from cisplatin, carboplatin, and oxaliplatin in human plasma ultrafiltrate. J Mass Spectrom 2006; 41:1186-1194

(79) Bruggeman SWM, Van Lohuizen M. Controling stem cell proliferation: CKIs at work. Cell Cycle 2006; 5:1281-1285

(80) Brummelkamp TR, Fabius AWM, Mullenders J, Madiredjo M, Velds A, Kerkhoven RM, Bernards R, Beijersbergen RL. An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors. Nat Chem Biol 2006; 2:202-206

(81) Buchwald G, Van Der Stoop P, Weichenrieder O, Perrakis A, Van Lohuizen M, Sixma TK. Structure and E3-ligase activity of the Ring-Ring complex of Polycomb proteins Bmi1 and Ring1b. EMBO J 2006; 25:2465-2474

(82) Buitelaar DR, Balm AJM, Antonini N, Van Tinteren H, Huitink JM. Cardiovascular and respiratory complications after major head and neck surgery. Head Neck 2006; 28:595-602

(83) Burgers JA, Olijve A, Baas P. [Chronic indwelling pleural catheter for malignant pleural effusion in 25 patients]
Ervaringen met een verblijfsdrain in de thorax bij 25 patienten met pleuritis carcinomatosa. Ned Tijdschr Geneeskd 2006; 150:1618-1623

(84) Buyse M, Loi S, Van't Veer L, Viale G, Delorenzi M, Glas AM, d'Assignies MS, Bergh J, Lidereau R, Ellis P, Harris A, Bogaerts J, Therasse P, Floore A, Amakrane M, Piette F, Rutgers E, Sotiriou C, Cardoso F, Piccart MJ, Decker N, Straehle C. Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J Natl Cancer Inst 2006; 98:1183-1192

(85) Cats A. Peri-operatieve chemotherapie bij het resectabel maagcarcinoom. Medische Oncologie 2006; 9:47-48

(86) Chanudet E, Zhou Y, Bacon CM, Wotherspoon AC, ller-Hermelink HK, Adam P, Dong HY, de Jong D, Li Y, Wei R, Gong X, Wu Q, Ranaldi R, Goteri G, Pileri SA, Ye H, Hamoudi RA, Liu H, Radford J, Du MQ. Chlamydia psittaci is variably associated with ocular adnexal MALT lymphoma in different geographical regions. J Pathol 2006; 209:344-351

(87) Chi JT, Wang Z, Nuyten DSA, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale A-L, Giaccia A, Longaker MT, Hastie T, Yang GP, Van De Vijver MJ, Brown PO. Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers. PLoS Medicine 2006; 3:395-409

(88) Choksi SP, Southall TD, Bossing T, Edoff K, de Wit E, Fischer B, van Steensel B, Micklem G, Brand AH. Prospero Acts as a Binary Switch between Self-Renewal and Differentiation in Drosophila Neural Stem Cells. Dev Cell 2006; 11:775-789

(89) Chuva de Sousa Lopes SM, Hassink RJ, Feijen A, Van Rooijen MA, Doevendans PA, Tertoolen L, Brutel de la Riviere A, Mummery CL. Patterning the heart, a template for human cardiomyocyte development. Dev Dyn 2006; 235:1994-2002

(90) Clark K, Langeslag M, Van Leeuwen B, Ran L, Ryazanov AG, Figdor CG, Moolenaar WH, Jalink K, Van Leeuwen FN. TRPM7, a novel regulator of actomyosin contractility and cell adhesion. EMBO J 2006; 25:290-301

(91) Corporaal S, Smit WM, Russel MGVM, van der Palen J, Boot H, Legdeur MCJC. Capecitabine, epirubicin and cisplatin in the treatment of oesophagogastric adenocarcinoma. Neth J Med 2006; 64:141-146

(92) Corten EML, Schellekens PPA, Bleys RLAW, Hage JJ, Kon M. The segmental pectoralis major free flap: Anatomical features of its vascular pedicle. Ann Plast Surg 2006; 56:82-86

(93) Crawford A, MacLeod M, Schumacher T, Corlett L, Gray D. Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells. J Immunol 2006; 176:3498-3506

(94) Crawford LJA, Walker B, Ovaa H, Chauhan D, Anderson KC, Morris TCM, Irvine AE. Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132. Cancer Res 2006; 66:6379-6386

(95) Creyghton MP, Roël G, Eichhorn PJA, Vredeveld LC, Destrée O, Bernards R. PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle. Proc Natl Acad Sci U S A 2006; 103:5397-5402

(96) Creyghton MP. Protein Phosphatase type 2A regulatory subunits and cancer. Utrecht: Universiteit Utrecht, 2006

(97) Cserni G, Bianchi S, Vezzosi V, Peterse H, Sapino A, Arisio R, Reiner-Concin A, Regitnig P, Bellocq JP, Marin C, Bori R, Penuela JM, Iturriagagoitia AC. The value of cytokeratin immunohistochemistry in the evaluation of axillary sentinel lymph nodes in patients with lobular breast carcinoma. J Clin Pathol 2006; 59:518-522

(98) Dannenberg J-H, te Riele HPJ. The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis. In: Kaldis P, editor. Cell Cycle Regulation. Berlin; Heidelberg; New York: Springer, 2006: 183-225

(99) Dantuma NP, Groothuis TAM, Salomons FA, Neefjes J. A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling. J Cell Biol 2006; 173:19-26

(100) David G, Dannenberg JH, Simpson N, Finnerty PM, Miao L, Turner GM, Ding Z, Carrasco R, DePinho RA. Haploinsufficiency of the mSds3 chromatin regulator promotes chromosomal instability and cancer only upon complete neutralization of p53. Oncogene 2006; 25:7354-7360

(101) Davies AHG, Larsson G, Ardill J, Friend E, Jones L, Falconi M, Bettini R, Koller M, Sezer O, Fleissner C, Taal B, Blazeby JM, Ramage JK. Development of a disease-specific quality of life questionnaire module for patients with gastrointestinal neuroendocrine tumours. Eur J Cancer 2006; 42:477-484

(102) de Bock GH, van der Hage JA, Putter H, Bonnema J, Bartelink H, Van De Velde CJ. Isolated loco-regional recurrence of breast cancer is more common in young patients and following breast conserving therapy: Long-term results of European Organisation for Research and Treatment of Cancer studies. Eur J Cancer 2006; 42:351-356

(103) De Boer P, Vos HR, Faber AW, Vos JC, Raue? HA. Rrp5p, a trans-acting factor in yeast ribosomem biogenesis, is an RNA-binding protein with a pronounced preference for U-rich sequences. RNA 2006; 12:263-271

(104) De Boer S, Dingemans JA, Huijbers EJM, Zych TR, Beijnen JH. Late cardiotoxicity after use of anthracycline: The reverse side of success. Pharm Weekbl 2006; 141:1154-1157

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