Reuven Agami, PhD
Group-leader,
Professor of Genetics and Pathology,
Head of Division of Gene Regulation,
The Netherlands Cancer Institute
Curriculum Vitae Reuven Agami
Since May 2017: Head of Division of oncogenomics, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Since 2018: Oncode PI
August 2014 - May 2017: Head of Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
June 2008 - August 2014: Head of Division of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Since 2008: Professor of Genetics and Patholog, Erasmus MC, Rotterdam, The Netherlands.
September 2005 - June 2008: Associated professor at the Division of Tumor Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
September 2001 - September 2005: Assistant professor at the Division of Tumor Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
June 1998 - September 2001: Post-doctoral fellowship at the Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
1993-1998: PhD at the Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot, Israel.
1991-1993: MSc at the Department of Membranes and Biophysics, The Weizmann Institute of Science, Rehovot, Israel.
1987-1991: BSc at Tel-Aviv University, Israel.
Honors and Awards Reuven Agami
1999: EMBO long-term fellowship.
2001: Netherlands Cancer Institute (AVL) award.
2002: Elected fellow of the central for biomedical genetics (CBG).
2002: Holding patent on pSUPER- vector based RNAi technology.
2004: Awarded European Young Investigator Award (EURYI).
2004: Awarded VIDI grant.
2004: Awarded EMBO young investigator award.
2006: Elected member of the young academy (DJA-KNAW).
2007: Awarded The Dr. Joseph Steiner Prize, Switzerland 2007 in Biel.
2008: Elected member of EMBO
2008: Elected member of the central for biomedical genetics (CBG).
2008: Awarded ERC startying grant "mirReg" on microRNA regulation
2009: Professor at the Genetics and Pathology departments of Erasmus Medical Center, Rotterdam
2010: ESCI Award Winner 2010, Basic/Translational Research ESCI website.
2011: VICI grant award, ZonMW website.
2012: Awarded ERC advanced project "enhReg" on enhancer RNAs. ERC advanced website.
2016: Member of the Academia Europaea
2017: Elected PI Oncode Institute.
2019: Awarded ERC advanced project "Breakborder" on structural regulatory elements. ERC advanced website.
Publications (for recent publications see "publication list")
Agami, R., Blandino, G. Oren, M. and Shaul, Y. (1999). Interaction of c-Abl and p73a and their collaboration to induce apoptosis.
Nature, 399, 809-813.
Agami, R. and Shaul, Y. (1998). The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFX1, a protein that binds the enhancers of several viruses and cell-cycle regulated genes.
Oncogene, 16 (14), 1779-88.
Katan, Y. Agami, R. and Shaul, Y. (1997). The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities.
Nucl. Acid Res., 25, 3621-28.
Dikstein, R., Agami, R., Heffetz, D. and Shaul, Y. (1996). P140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues.
Proc. Natl. Acad. Sci., 93, 2387-2391.
Agami, R., Aly, R., Halman, S. and Shapira, M. (1994). Functional analysis of cis-acting DNA elements required for expression of the SL RNA gene in the parasitic protozoan Leishmania amazonensis.
Nucl. Acid Res., 22, 1959-65.
Michaeli, S., Agami, R. and Shapira, M. (1993). Leishmania mexicana amazonensis: effect of heat shock on the spliced leader RNA and its ribonucleoprotein particle SL RNP.
Exp. Parasitol., 76, 59-67.
Agami, R. and Shapira, M. (1992). Nucleotide sequence of the spliced leader RNA gene from Leishmania mexicana amazonensis. Nucl. Acid Res., 20, 1804.